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2016 Scholars' Abstract Award Finalists and Winner

IARS 2016 Annual Meeting and International Science Symposium

Improving Health Through Discovery and Education
May 21-24, 2016 • San Francisco, CA

SCH-1: A NOVEL TREATMENT FOR MEMORY IMPAIRMENT AFTER CONCUSSION IN MICE
S. Avramescu1, H. Sheng2, D. Wang3, B. A. Orser4
1Department of Anesthesia, University of Toronto and Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 2Department of Human Biology, University of Toronto, Toronto, ON, Canada, 3Department of Physiology, University of Toronto, Toronto, ON, Canada, 4Department of Anesthesia and Physiology, University of Toronto, Ontario, ON, Canada

SCH-2: FTY720 PREVENTS OXLDL INDUCED MACROPHAGE TRAPPING VIA REDUCTION OF HEME OXYGENASE 1 EXPRESSION IN ATHEROSCLEROTIC BURDEN MICE
H. Janssen1, J. Larmann1, S. Immenschuh2, G. Theilmeier3
1Anesthesia, University Hospital Heidelberg, Heidelberg, Germany, 2Tranfusion Medicine, Medical School Hannover, Hannover, Germany, 3Anesthesia, Carl von Ossietzky University Oldenburg, Oldenburg, Germany

SCH-3: TRPA1 ACTIVATION REDUCES MYOCARDIAL INJURY IN RODENTS
Y. Lu, H. Piplani, C. M. Hurt, S. L. McAllister, E. R. Gross
Department of Anesthesiology, Stanford University, Stanford, CA

SCH-4: PATTERNS OF USE OF A CLINICAL ANESTHESIA CALCULATOR AND DECISION SUPPORT TOOL IN AN INTERNATIONAL PROVIDER POPULATION
V. O'Reilly-Shah
Department of Anesthesiology, Division of Pediatric, Emory University School of Medicine, Atlanta, GA

SCH-5: EFFECTIVENESS OF HYPOTENSION TREATMENT BETWEEN BOLUS AND CONTINUOUS INFUSION OF PHENYLEPHRINE: A RANDOMIZED COMPARISON USING AN IN SILICA SIMULATION
S. S. Pfost1, N. Ribeiro Marques1, J. Wolf1, G. Cao2, T. Luspay2, K. Grigoriadis2, G. Kramer1
1Anesthesiology, University of Texas Medical Branch, Galveston, TX, 2Mechanical Engineering, University of Houston, Houston, TX

SCH-6: GOAL DIRECTED EARLY MOBILIZATION REDUCES ICU LENGTH OF STAY AND IMPROVES FUNCTIONAL MOBILITY: AN INTERNATIONAL CONTROLLED MULTI CENTER, RANDOMIZED, TRIAL (SOMS TRIAL)
S. J. Schaller1, K. Waak2, T. Edrich3, J. M. Walz4, M. Blobner1, M. Eikermann5
1Klinik für Anaesthesiologie, Technische Universitaet Muenchen, Munich, Germany, 2Department of Physical and Occupational Therapy, Massachusetts General Hospital, Boston, MA, 3Abteilung für Anästhesie und Operative Intensivmedizin, Klinikum Landkreis Erding, Paracelsus Medical Univ, Erding, Germany, 4Department of Anesthesiology and Perioperative Medicine, UMass Memorial Healthcare, Worcester, MA, 5Anesthesia, Critical Care & Pain Medicine, MGH, Boston, MA

SCH-7: TOWARDS NEUROPHYSIOLOGICAL BIOMARKERS OF BRAIN VULNERABILITY: FRONTAL ALPHA WAVES PREDICT THE PROPENSITY FOR INTRAOPERATIVE BURST SUPPRESSION
Y. R. Shao1, K. J. Pavone2, O. Akeju2, E. N. Brown2, P. Purdon2
1Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA, 2Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA

SCH-8: INCREASING UPTAKE OF COGNITIVE AIDS IN CRITICAL EVENTS
A. Siddiqui1, E. Ng2, T. Everett2
1Department of Anesthesia, University of Toronto, Toronto, ON, Canada, 2Department of Anesthesia and Pain Medicine, University of Toronto - Hospital for Sick Children, Toronto, ON, Canada

SCH-9: A NOVEL ASSOCIATION BETWEEN HIGH DENSITY LIPOPROTEIN LEVELS AND THE RISK OF ACUTE KIDNEY INJURY AFTER CARDIAC SURGERY
L. Smith1, D. K. Smith2, M. F. Linton3, F. T. Billings4
1Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, 2Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 3Departments of Medicine and Pharmacology, Division of Cardiovascular Medicine, Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN, 4Anesthesiology, Vanderbilt University, Nashville, TN

SCH-10: PERIOPERATIVE TLR4 MODULATION IN A MOUSE MODEL OF SURGICAL TRAUMA: A SYSTEMS-WIDE ANALYSIS BY SINGLE-CELL MASS CYTOMETRY
V. L. Tawfik, E. A. Ganio, N. Aghaeepour, M. S. Angst, D. J. Clark, B. Gaudilliere
Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, CA

SCH-11: INHIBITION OF FREE FATTY ACID RECEPTOR GPR40 ABOLISHES CARDIOPROTECTION CONFERRED BY INTRALIPID IN TWO RODENT MODELS OF BUPIVACAINE CARDIOTOXICITY AND ISCHEMIA REPERFUSION INJURY
S. Umar, J. Li, P. Partownavid, A. Mahajan, M. Eghbali
Anesthesiology and Perioperative Medicine, UCLA, Los Angeles

SCH-12: ALTERING BUFFER Ca2+ AND pH STIMULATIONS ACTIVIATION OF MITOCHONDRIAL Ca2+/H+ EXCHANGER
M. Boswell1, C. A. Blomeyer PhD1,4, J. S. Heisner BS1, M. Aldakkak MD1, A K.S. Camara PhD1, D. F. Stowe MD, PhD2,3
1Anesthesiology Department, Medical College of Wisconsin, 2Department of Biomedical Engineering, Marquette University, 3Zablocki VA Medical Center, 4University of Wuerzburg, Germany
MARC 2016 IARS Award in Basic Science

*Scholars' Abstract Award Winner*
SCH-13: NEURON-TARGETED CAVEOLIN-1 DELAYS ONSET AND EXTENDS SURVIVAL IN THE hSOD1G93A MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS
B. Illum, A. Sawada, M. J. Egawa, H. Patel, D. Roth, M. Pearn, P. M. Patel, B. P. Head, D. Roth
University of California, San Diego, CA
WARC 2016 Meeting Award Winner

SCH-14: INFUSION SYSTEM ARCHITECTURE IMPACTS THE ABILITY OF INTENSIVE CARE NURSES TO MAINTAIN HEMODYNAMIC STABILITY IN A LIVING SWINE SIMULATOR
R. Govindaswamy1,M.J. Pezone2, R.A.Peterfreund2, M.Y Maslov2, M. Lovich2
1St. Elizabeth's Medical Center, Tufts University, Brighton, MA, 2St. Elizabeth's Medical Center Brighton, MA, Massachusetts General Hospital, Boston, MA
NEARC 2016 Award for Original Investigations in Clinical Research

SCH-15: PERIOPERATIVE AIRWAY CHANGES AND THEIR RETURN TO BASELINE IN PATIENTS UNDERGOING ELECTIVE SURGERY IN THE PRONE AND TRENDELENBURG POSITIONS: EARLY DATA
F. Sawyer1, T. Phan1, I. Moreno Duarte2, I. Bonney2, R. Schumann2
1School of Medicine, Tufts University, Boston, MA, 2Department of Anesthesiology, Tufts Medical Center, Boston, MA
NEARC 2016 Award for Original Investigations in Clinical Research

SCH-16: SUDDEN SENSORINEURAL HEARING LOSS AFTER GENERAL ANESTHESIA FOLLOWING NON-CARDIOPULMONARY AND NON-OTOLOGIC GENERAL SURGERY: TWO CASE REPORTS AND A REVIEW OF THE LITERATURE
S.S. Das
Department of Anesthesia, Ochsner Clinic Foundation, New Orleans, LA
GAARRC 2015 Award

SCH-17: MASSIVE CARDIAC THROMBOSIS AND DISSEMINATED INTRAVASCULAR COAGULOPATHY IN A PATIENT WITH RETAINED DEAD FETUS SYNDROME
S. Vallancourt, B. Mohamed, L. Davies
University of Florida, Gainesville, FL
GAARRC 2015 Award for Case Presentation Category and Best Overall Presentation

SCH-18: OPTIMIZING INTRAOPERATIVE ANALGESIC DRUG INJECTIONS AT THE SURGICAL WOUND SITE TO REDUCE POSTOPERATIVE PAIN AFTER KNEE SURGERY IN RATS
Shereef Yassin
Rush University Medical Center, Chicago, IL
MARC 2015 IARS Award in Basic Science